Aptamer Nanoconstructs Crossing Human BBB Discovered via Microphysiological System-Based SELEX Technology
Their findings have been published in the April 2023 issue of ACS Nano.
Abstract Blood–brain barrier (BBB) remains one of the critical challenges in developing neurological therapeutics. Short single-stranded DNA/RNA nucleotides forming a three-dimensional structure, called aptamers, have received increasing at... Read More
Their findings have been published in the December 2022 issue of Biomaterials.
Abstract The basement membrane (BM) of the blood-brain barrier (BBB), a thin extracellular matrix (ECM) sheet underneath the brain microvascular endothelial cells (BMECs), plays crucial roles in regulating the unique physiological barrier f... Read More