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Home Cancer research

New Gene Editing Technology Enables Selective Destruction of Cancer Cell DNA Using Fewer Targets

This study was published in Cancer Research, the official journal of the American Association for Cancer Research (AACR) on August 1, 2025.

New Gene Editing Technology Enables Selective Destruction of Cancer Cell DNA Using Fewer Targets

Abstract Triggering cancer cell death by inducing DNA damage is the primary aim of radiotherapy; however, normal cells are also damaged. In this study, we showed that delivery of only four synthetic guide RNAs with Cas9 endonuclease efficie... Read More

Sep 17, 2025 By JooHyeon Heo Research
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New Study Unveils How A Natural Compound from Sea Squirts Combats Cancer

Scientists have deciphered how trabectedin outsmarts cancer cells’ DNA repair mechanism, paving the way for tailored treatments.

Their findings have been published in the February 2024 issue of Nature Communications.

New Study Unveils How A Natural Compound from Sea Squirts Combats Cancer

Numerous anti-cancer drugs function by targeting the DNA within cancerous cells, halting their proliferation. Yet, cancer cells occasionally develop mechanisms to repair the damage inflicted by these drugs, diminishing their effectiveness.... Read More

Mar 13, 2024 By JooHyeon Heo Research
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Scientists develop New Platform Technology for Personalized Cancer Therapy

The work by Distinguished Professor Kyungjae Myung's team has been published in PNAS.

A new therapy called CINDELA (Cancer-Specific InDel Attacker) employs CRISPR-Cas9 to kill cancer cells without affecting normal tissues.

Scientists develop New Platform Technology for Personalized Cancer Therapy

Diagnosis of cancers may be one of the worst news to patients and their families. Conventional treatment options such as radiation and chemotherapies often kill not only cancer cells but also normal cells, which results in painful side effe... Read More

Feb 28, 2022 By IBS Communications Team Research
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