Abstract Triggering cancer cell death by inducing DNA damage is the primary aim of radiotherapy; however, normal cells are also damaged. In this study, we showed that delivery of only four synthetic guide RNAs with Cas9 endonuclease efficie... Read More
Abstract Extracorporeal hemoadsorption for treating bacteremia has exhibited limited success due to the lack of a clear strategy for effectively bringing bacterial cells into contact with the surface and universal bacteria-capturing substan... Read More
SuPine Therapeutics Inc., a biotech startup founded by Professor Jeong Beom Kim of the Department of Biomedical Engineering at UNIST, was selected as the final winner of the 2025 SelectUSA World Finals Pitching Competition, held in Washingt... Read More
Abstract Nonlinear microscopy provides excellent depth penetration and axial sectioning for 3D imaging, yet widespread adoption is limited by reliance on expensive ultrafast pulsed lasers. This work circumvents such limitations by employing... Read More
Abstract Heterogeneity and the absence of a tumor microenvironment (TME) in traditional patient-derived organoid (PDO) cultures limit their effectiveness for clinical use. Here, Embedded Bioprinting-enabled Arrayed PDOs (Eba-PDOs) featuring... Read More
In celebration of International Women’s Day on March 8, a prominent article published by Nature has recognized Professor Yoon-Kyoung Cho, a leading biomedical engineer at UNIST. The article, titled “Behind Every Great Woman in S... Read More
Abstract Fast and accurate identification of pathogenic microbes in patient samples is crucial for the timely treatment of acute infectious diseases such as sepsis. The fluorescence in situ hybridization (FISH) technique allows the rapid de... Read More
Abstract Tumor-derived extracellular vesicle (tEV)-associated RNAs hold promise as diagnostic biomarkers, but their clinical use is hindered by the rarity of tEVs among nontumor EVs. Here, we present EV-CLIP, a highly sensitive droplet-base... Read More
As individuals age, muscle regeneration becomes increasingly critical for maintaining health and quality of life. To address this challenge, there is a pressing need for advanced biotechnological solutions. In response, UNIST has establishe... Read More
Abstract Proteins, inherently biocompatible and biodegradable, face a challenge in forming stable hydrogels without external chemical crosslinkers. Here, we construct a ring-shaped trimeric SpyTag-fused Proliferating Cell Nuclear Antigen Pr... Read More
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