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Home Sangjoon Lee

New Study Identifies AIM2 as a Key Inflammasome Sensor in MPXV Infection

Their findings were published in the Cellular & Molecular Immunology on November 12, 2025.

New Study Identifies AIM2 as a Key Inflammasome Sensor in MPXV Infection

Abstract Monkeypox, a zoonotic disease caused by the monkeypox virus (MPXV), has significant global public health implications. Inflammasomes serve as crucial components of the innate immune system, detecting pathogens and triggering cell d... Read More

Dec 08, 2025 By JooHyeon Heo Research
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From COVID-19 to Alcoholic Liver Disease: UNIST Spearheads Development of ZBP1 Inhibitors

Professor SangJoon Lee's team has been selected by the KDDF for their research on developing therapeutics for alcoholic liver disease treatment.

From COVID-19 to Alcoholic Liver Disease: UNIST Spearheads Development of ZBP1 Inhibitors

As Z-DNA binding protein 1 (ZBP1) has emerged as a promising target for simultaneously targeting infectious and inflammatory diseases, UNIST has been consecutively selected for national research and development projects to accelerate the de... Read More

Jun 26, 2025 By JooHyeon Heo People
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Unraveling the Role of Multi-Sensor Inflammatory Control Complexes in Innate Immunity

The findings of this research have been published in the March 2024 issue of Trends in Immunology.

Unraveling the Role of Multi-Sensor Inflammatory Control Complexes in Innate Immunity

Abstract Pathogens elicit complex mammalian immune responses by activating multiple sensors within inflammasomes, which recognize diverse pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). This... Read More

Mar 25, 2024 By JooHyeon Heo Research
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Novel Therapeutic Approach for Treatment of ‘Cytokine Storm’ Gets Support from the Circle Foundation!

Professor Sangjun Lee (Dept. of Biological Sciences) has been selected for the 2023 Innovative Science and Technology Centers and Programs by the Circle Foundation.

Novel Therapeutic Approach for Treatment of ‘Cytokine Storm’ Gets Support from the Circle Foundation!

The Circle Foundation (formerly known as the Ahn Cheol-Soo Foundation) is actively supporting the development of technology to treat high-risk novel viral infectious diseases, including COVID-19. As part of their efforts, Professor Sangjun... Read More

Dec 11, 2023 By JooHyeon Heo People
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