Abstract Recently, targeted protein degradation (TPD) strategies have emerged as a promising solution to tackle undruggable proteins. While most TPD strategies target intracellular proteins, limited options exist for targeting extracellular... Read More
Abstract Targeted drug delivery systems based on metal–organic frameworks (MOFs) have progressed tremendously since inception and are now widely applicable in diverse scientific fields. However, translating MOF agents directly to targeted d... Read More
Four exceptional UNIST graduate students have been honored with the prestigious 2024 Asan Foundation Medical Bioscience Scholarship, a distinguished accolade bestowed upon the nation’s most outstanding graduate students in medical bio... Read More
Abstract Senolytics, which eliminate senescent cells from tissues, represent an emerging therapeutic strategy for various age-related diseases. Most senolytics target antiapoptotic proteins, which are overexpressed in senescent cells, limit... Read More
Abstract Lysosomes remain powerful organelles and important targets for cancer therapy because cancer cell proliferation is greatly dependent on effective lysosomal function. Recent studies have shown that lysosomal membrane permeabilizatio... Read More
Abstract Intramitochondrial supramolecular assembly can be a new therapeutic strategy for treating cancer because mitochondria are the key for virtually all facets of the tumorigenesis. However, the in vivo applications of mitochondria-targ... Read More
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