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Home CGI

New Gene Editing Technology Enables Selective Destruction of Cancer Cell DNA Using Fewer Targets

This study was published in Cancer Research, the official journal of the American Association for Cancer Research (AACR) on August 1, 2025.

New Gene Editing Technology Enables Selective Destruction of Cancer Cell DNA Using Fewer Targets

Abstract Triggering cancer cell death by inducing DNA damage is the primary aim of radiotherapy; however, normal cells are also damaged. In this study, we showed that delivery of only four synthetic guide RNAs with Cas9 endonuclease efficie... Read More

Sep 17, 2025 By JooHyeon Heo Research
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Breakthrough Research Uncovers Key Mechanism in DNA Repair Process

The work by Distinguished Professor Kyungjae Myung has been published in the online version of Nucleic Acids Res. on September 22, 2023.

Breakthrough Research Uncovers Key Mechanism in DNA Repair Process

Abstract Homologous recombination (HR) requires bidirectional end resection initiated by a nick formed close to a DNA double-strand break (DSB), dysregulation favoring error-prone DNA end-joining pathways. Here we investigate the role of th... Read More

Oct 24, 2023 By JooHyeon Heo Research
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Researchers Solve Puzzle of How Cells Select DNA Damage Repair Pathways

Distinguished Professor Kyungjae Myung's research team discovers a new function of mismatch repair protein MSH2-MSH3 in DNA double-strand break repair.

Their findings have been published in the May 2023 issue of Nucleic Acids Research.

Researchers Solve Puzzle of How Cells Select DNA Damage Repair Pathways

DNA is well known as the blueprint of life, necessary for an organism to facilitate living processes. DNA can be damaged by various factors such as radical metabolites, radiation, and some toxic chemicals. As DNA is a molecule consisting of... Read More

May 16, 2023 By JooHyeon Heo Research
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UNIST, Boasting Highly Potential Faculties with Spirit “We Can Do It!”

[WHY UNIST] Prof. KyungJae Myung, School of Life Sciences

UNIST, Boasting Highly Potential Faculties with Spirit “We Can Do It!”

“UNIST provides a supportive environment for ambitious young scientists,” says Dr. Kyungjae Myung who is Distinguished Professor in the School of Life Sciences at UNIST. For future students considering a degree at UNIST, Dr. Myung explains... Read More

Jul 01, 2015 By JooHyeon Heo People
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UNIST to Host International Symposium on Genomic Integrity

The 1st CGI International Symposium, held at UNIST from May 27 to 30, 2015

Dr. Kyungjae Myung, Director of the Center for Genomic Integrity (CGI) at the 1st CGI International Symposium.

World-renowned experts in genomic integrity convened on May 27 at the Low Dimensional Carbon Materials Building of UNIST to discuss the current challenges and opportunities in genomic research and medicine. The 1st CGI International Symposi... Read More

Jun 02, 2015 By JooHyeon Heo News
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UNIST to Host 3 IBS Research Centers

UNIST, one of the world's foremost graphene R&D institutions

UNIST to Host 3 IBS Research Centers

On April 27, UNIST held a ceremony not only to mark the completion of new IBS Center for Multi-Dimensional Carbon Materials (CMCM), but also to celebrate the establishment of two other IBS research centers on campus. During the course of th... Read More

Apr 27, 2015 By JooHyeon Heo Research
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New Director for IBS Research Center at UNIST

Dr. Kyungjae Myung, selected to head the Center for Genomic Integrity (CGI) at the UNIST campus

Dr. Kyungjae Myung (School of Life Sciences), the new director for the Center for Genomic Integrity (CGI)

In recent years, UNIST has hosted three IBS campus research centers, led by world-class scientists, thereby capturing the attention of scientists worldwide with its potential to become one of the world’s top 10 science and technology univer... Read More

Jan 02, 2015 By JooHyeon Heo Research
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