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Home Ja Yil Lee

New Discovery Reveals How Two Proteins Collaborate to Detect UV-Induced DNA Damage

The findings were published online in the esteemed journal Nucleic Acids Research (Impact Factor: 16.6) on June 18, 2025.

New Discovery Reveals How Two Proteins Collaborate to Detect UV-Induced DNA Damage

Abstract Ultraviolet-induced DNA lesions are removed by the nucleotide excision repair (NER) pathway. In global-genome NER (GG-NER), XPC-RAD23B recognizes the lesions and initiates NER. However, cyclobutane pyrimidine dimers (CPDs), which d... Read More

Jul 14, 2025 By JooHyeon Heo Research
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World’s First Real-Time Visualization of DNA Replication Unveils Unprecedented Scientific Insights

Their findings have been published in the online version of Nucleic Acids Research on November 22, 2023.

World’s First Real-Time Visualization of DNA Replication Unveils Unprecedented Scientific Insights

Abstract R-loops are three-stranded nucleic acid structures that can cause replication stress by blocking replication fork progression. However, the detailed mechanism underlying the collision of DNA replication forks and R-loops remains el... Read More

Nov 30, 2023 By JooHyeon Heo Research
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Researchers Solve Puzzle of How Cells Select DNA Damage Repair Pathways

Distinguished Professor Kyungjae Myung's research team discovers a new function of mismatch repair protein MSH2-MSH3 in DNA double-strand break repair.

Their findings have been published in the May 2023 issue of Nucleic Acids Research.

Researchers Solve Puzzle of How Cells Select DNA Damage Repair Pathways

DNA is well known as the blueprint of life, necessary for an organism to facilitate living processes. DNA can be damaged by various factors such as radical metabolites, radiation, and some toxic chemicals. As DNA is a molecule consisting of... Read More

May 16, 2023 By JooHyeon Heo Research
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UNIST Biology Researcher Honored with the 2023 KPS Young Biophysicist Awards!

The award ceremony took place at the 2023 Subcommittee Meeting of the Korean Physical Society on April 19, 2023.

UNIST Biology Researcher Honored with the 2023 KPS Young Biophysicist Awards!

A researcher, affiliated with UNIST has recently been honored with the ‘2023 Young Biophysicist Awards‘ by the Korean Physical Society (KPS). The recipient is Na Young Choen (Advisor: Professor Ja Yil Lee) from the Department of... Read More

May 04, 2023 By JooHyeon Heo People
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