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Dual-Modulated Release of a Cytotoxic Photosensitizer Using Photogenerated Reactive Oxygen Species and Glutathione

Their findings have been published in the September 2022 issue of Angewandte Chemie International Edition.

Dual-Modulated Release of a Cytotoxic Photosensitizer Using Photogenerated Reactive Oxygen Species and Glutathione

Abstract Reversible thiol-disulfide exchange chemistry is of particular interest in drug delivery systems. However, high levels of glutathione (GSH) in cancer cells are hard to distinguish from GSH in normal cells, resulting in unmanageable... Read More

Sep 15, 2022 By JooHyeon Heo Research
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TRAIL & EGFR Affibody Dual-display on Protein Nanoparticle Synergistically Suppresses Tumor Growth

Their findings have been published in the June 2022 issue of J. Control. Release.

TRAIL & EGFR Affibody Dual-display on Protein Nanoparticle Synergistically Suppresses Tumor Growth

Abstract The TNF-related apoptosis-inducing ligand (TRAIL) is a promising anticancer drug candidate because it selectively binds to the proapoptotic death receptors, which are frequently overexpressed in a wide range of cancer cells, subseq... Read More

Sep 02, 2022 By JooHyeon Heo Research
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Structural Basis for Mitoguardin-2 Mediated Lipid Transport at ER-mitochondrial Membrane Contact Sites

Their findings have been published in the June 2022 issue of Nature Communications.

Structural Basis for Mitoguardin-2 Mediated Lipid Transport at ER-mitochondrial Membrane Contact Sites

Abstract The endoplasmic reticulum (ER)-mitochondria contact site (ERMCS) is crucial for exchanging biological molecules such as phospholipids and Ca2+ ions between these organelles. Mitoguardin-2 (MIGA2), a mitochondrial outer membrane pro... Read More

Aug 03, 2022 By JooHyeon Heo Research
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New Study Presents Self-Assembled Artificial Nanocilia Actuators

Their findings have been published in Advanced Materials as the front cover paper.

New Study Presents Self-Assembled Artificial Nanocilia Actuators

Abstract Self-assembly of nanoparticles (NPs) is a powerful route to constructing higher-order structures. However, the programmed self-assembly of NPs into non-close-packed, 3D, shape-morphing nanocilia arrays remains elusive, whereas dyna... Read More

Jul 25, 2022 By JooHyeon Heo Research
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Rapid Access to Polycyclic N-heteroarenes from Unactivated, Simple Azines via Base-promoted Minisci-type Annulation

Their findings have been published in Nature Communications.

Rapid Access to Polycyclic N-heteroarenes from Unactivated, Simple Azines via Base-promoted Minisci-type Annulation

The research groups of Professors Sung You Hong and Jan-Uwe Rohde of the UNIST Chemistry Department have developed a one-step synthetic method to access ‘nitrogen-containing polyaromatic hydrocarbons’ from simple azines, which have applicat... Read More

Jul 08, 2022 By JooHyeon Heo Research
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Giant Bulk Photovoltaic Effect Driven by the Wall-to-Wall Charge Shift in WS2 Nanotubes

Their findings have been published in Nature Communications.

Giant Bulk Photovoltaic Effect Driven by the Wall-to-Wall Charge Shift in WS2 Nanotubes

Abstract The intrinsic light–matter characteristics of transition-metal dichalcogenides have not only been of great scientific interest but have also provided novel opportunities for the development of advanced optoelectronic devices. Among... Read More

Jul 06, 2022 By JooHyeon Heo Research
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Promising New Avenue to Tackle Obesity and Related Metabolic Diseases

Their findings have been published in the June 2022 issue of PNAS.

Promising New Avenue to Tackle Obesity and Related Metabolic Diseases

Abstract β-adrenergic receptor (β-AR) signaling plays predominant roles in modulating energy expenditure by triggering lipolysis and thermogenesis in adipose tissue, thereby conferring obesity resistance. Obesity is associated with diminish... Read More

Jul 01, 2022 By JooHyeon Heo Research
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Alkali Extraction to Detoxify Rice Husk-Derived Silica and Increase Its Biocompatibility

Their findings have been published in the online issue of the ACS Sustainable Chemistry & Engineering.

Alkali Extraction to Detoxify Rice Husk-Derived Silica and Increase Its Biocompatibility

A research team, led by Professor Robert J. Mitchell, in collaboration with Dr. Jin Hyung Lee and Dr. Jinyoung Chun from Korea Institute of Ceramic Engineering & Technology (KICET) pursued a novel bio-application by identifying syntheti... Read More

Jun 29, 2022 By JooHyeon Heo Research
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1,700-year-old Korean Genomes Show Genetic Heterogeneity in Three Kingdoms Period Gaya

Their findings have been published online in the June 2022 issue of Current Biology.

1,700-year-old Korean Genomes Show Genetic Heterogeneity in Three Kingdoms Period Gaya

Eight 1,700-year-old genomes dated to the Three Kingdoms period have shown that ancient Koreans from the Gaya confederacy were more diverse than the present-day Korean population. This study presents the first ever Korean genomes from the T... Read More

Jun 23, 2022 By JooHyeon Heo Research
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Monolayer Molybdenum Disulfide Wwitches for 6G Communication Systems

Their findings have been published in the June 2022 issue of Nature Electronics, a sister publication to Nature.

Monolayer Molybdenum Disulfide Wwitches for 6G Communication Systems

A new semiconductor device for applications in 6G data communication has been developed. It has attracted considerable attention, capable of processing digital signals significantly faster and being more energy-efficient than anything avail... Read More

Jun 20, 2022 By JooHyeon Heo Research
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