With obesity rates projected to continue rising globally, there is an urgent need to understand the intricate mechanisms that contribute to metabolic diseases such as diabetes. Addressing this critical issue head-on, Professor Jiyoung Park... Read More
Abstract Replication protein A (RPA), a eukaryotic single-stranded DNA (ssDNA) binding protein, dynamically interacts with ssDNA in different binding modes and plays essential roles in DNA metabolism such as replication, repair, and recombi... Read More
Abstract Entosis is a non-apoptotic cell death process that forms characteristic cell-in-cell structures in cancers, killing invading cells. Intracellular Ca2+ dynamics are essential for cellular processes, including actomyosin contractilit... Read More
Abstract Coronaviruses target ciliate cells causing the loss of cilia, acute rhinorrheas, and other ciliopathies. The loss of ciliary function may help the virus infect, replicate, and spread. However, the molecular mechanisms by which coro... Read More
Abstract Vac8, a yeast vacuolar protein with armadillo repeats, mediates various cellular processes by changing its binding partners; however, the mechanism by which Vac8 differentially regulates these processes remains poorly understood. V... Read More
A researcher, affiliated with UNIST has recently been honored with the ‘2023 Young Biophysicist Awards‘ by the Korean Physical Society (KPS). The recipient is Na Young Choen (Advisor: Professor Ja Yil Lee) from the Department of... Read More
Abstract Integration of single-cell RNA sequencing data between different samples has been a major challenge for analyzing cell populations. However, strategies to integrate differential expression analysis of single-cell data remain underi... Read More
Abstract Exosomes transport a variety of macromolecules and modulate intercellular communication in physiology and disease. However, the regulation mechanisms that determine exosome contents during exosome biogenesis remain poorly understoo... Read More
Abstract Hyperglycemia is a risk factor for breast cancer-related morbidity and mortality. Hyperglycemia induces Neuregulin 1 (Nrg1) overexpression in breast cancer, which subsequently promotes tumor progression. However, molecular mechanis... Read More
HyunWoo Kim, a graduate student (Advisor: Professor Changwook Lee) in the Department of Biological Sciences at UNIST has recently been honored with the prestigious 2023 Asan Foundation Medical Bioscience Scholarship in recognition of his ex... Read More
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