Abstract The SARS-CoV-2 pandemic has had an unprecedented impact on global public health and the economy. Although vaccines and antivirals have provided effective protection and treatment, the development of new small molecule-based antivir... Read More
Abstract Homologous recombination (HR) requires bidirectional end resection initiated by a nick formed close to a DNA double-strand break (DSB), dysregulation favoring error-prone DNA end-joining pathways. Here we investigate the role of th... Read More
DNA is well known as the blueprint of life, necessary for an organism to facilitate living processes. DNA can be damaged by various factors such as radical metabolites, radiation, and some toxic chemicals. As DNA is a molecule consisting of... Read More
Abstract TRAIP is a key factor involved in the DNA damage response (DDR), homologous recombination (HR) and DNA interstrand crosslink (ICL) repair. However, the exact functions of TRAIP in these processes in mammalian cells are not fully un... Read More
Diagnosis of cancers may be one of the worst news to patients and their families. Conventional treatment options such as radiation and chemotherapies often kill not only cancer cells but also normal cells, which results in painful side effe... Read More
Three UNIST graduate students have been awarded the prestigious 2021 Asan Foundation Medical Bioscience Scholarship, an annual award given to the nation’s top graduate students in medical bioscience. The Asan Foundation Medical Biosci... Read More
Harvard Medical School Professor William G. Kaelin Jr., one of the 2019 Nobel Laureates in Physiology or Medicine, is visiting UNIST on Tuesday, November 5, 2019. This visit is held on an invitation from Director Kyungjae Myung of IBS Cente... Read More
DNA replication is essential for living organisms to faithfully deliver genetic information from parental cells to daughter cells. Many proteins are assembled on the parental DNA to work as replication machineries. Among them, the prolifera... Read More
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